Fujimura N, Namba H, Tsunoda K, Kawamata T, Taki K, Igarashi M, Namiki A
Department of Anesthesiology, Sapporo Medical University, Hokkaido, Japan.
Masui. 1996 Apr;45(4):428-32.
We investigated the effect of epidural buprenorphine on diaphragmatic function using respiratory inductive plethysmography (RIP) in seven healthy patients after upper abdominal surgery. After surgery, changes of rib cage contribution to tidal volume (%RC) increased significantly from 25.3 +/- 7.3 (mean +/- SD) to 50.7 +/- 14.8% (P < 0.05). After the injection of epidural buprenorphine, visual analogue scale (VAS) score decreased significantly from 8.3 to 3.3 (P < 0.05). But, %RC was unchanged compared to the value before the injection. These results indicate that pain relief by epidural buprenorphine does not improve diaphragmatic function after upper abdominal surgery.
我们使用呼吸感应体积描记法（RIP）研究了硬膜外注射丁丙诺啡对7例上腹部手术后健康患者膈肌功能的影响。术后，胸廓对潮气量的贡献率（%RC）从25.3±7.3（均值±标准差）显著增加至50.7±14.8%（P<0.05）。硬膜外注射丁丙诺啡后，视觉模拟评分（VAS）从8.3显著降至3.3（P<0.05）。但是，与注射前的值相比，%RC没有变化。这些结果表明，硬膜外注射丁丙诺啡缓解疼痛并不能改善上腹部手术后的膈肌功能。
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