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作为其他机械辅助手段桥梁的主动脉外球囊反搏的实验研究

Experimental study of extraaortic balloon counterpulsation as a bridge to other mechanical assists.

作者信息

Odaguchi H, Yozu R, Kashima I, Mitsumaru A, Kanda K, Tsutsui N, Tsutsui Y, Kawada S

机构信息

Department of Surgery, Keio University, Tokyo, Japan.

出版信息

ASAIO J. 1996 May-Jun;42(3):190-4.

PMID:8725686
Abstract

A special extraaortic balloon was developed that can be placed around the ascending aorta. This balloon can easily support the heart temporarily in a median sternotomy field, especially in cases in which it is difficult to use intraaortic balloon pumping because of peripheral arterial disease. The goal of this study was to judge the applicability of this extraaortic balloon counterpulsation. An extraaortic balloon was placed around the ascending aorta of eight adult canines. Two heart failure models were used in this study: group A-moderate heart failure; group B-severe heart failure. In group A, the aortic systolic pressure was significantly reduced (9.3%, p < 0.01), but in group B, there was no significant change. In group A, there was a significant increase in cardiac output (12.0%, p < 0.01), but in group B, there was no significant change. The endocardial viability ratio in both groups significantly increased (group A: 11.3%, p < 0.01; group B: 11.9%, p < 0.05). An extraaortic balloon around the ascending aorta is easily applicable through a median sternotomy, and can be used as a bridge to more powerful mechanical assists when intraaortic balloon pumping cannot be used.

摘要

一种特殊的主动脉外球囊被研发出来,它可以放置在升主动脉周围。这种球囊能够在正中胸骨切开术视野中轻松地临时支持心脏,特别是在因外周动脉疾病而难以使用主动脉内球囊反搏的情况下。本研究的目的是判断这种主动脉外球囊反搏的适用性。在八只成年犬的升主动脉周围放置了一个主动脉外球囊。本研究使用了两种心力衰竭模型:A组——中度心力衰竭;B组——重度心力衰竭。在A组中,主动脉收缩压显著降低(9.3%,p<0.01),但在B组中,没有显著变化。在A组中,心输出量显著增加(12.0%,p<0.01),但在B组中,没有显著变化。两组的心内膜存活比率均显著增加(A组:11.3%,p<0.01;B组:11.9%,p<0.05)。升主动脉周围的主动脉外球囊通过正中胸骨切开术很容易应用,并且在无法使用主动脉内球囊反搏时可作为通向更强大机械辅助的桥梁。

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