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小鼠胎儿内部结构的磁共振成像。

Magnetic resonance imaging of the internal structure of the mouse fetus.

作者信息

Orita J, Sato E, Saburi S, Nishida T, Toyoda Y

机构信息

Department of Reproductive and Developmental Biology, University of Tokyo, Japan.

出版信息

Exp Anim. 1996 Apr;45(2):171-4. doi: 10.1538/expanim.45.171.

DOI:10.1538/expanim.45.171
PMID:8726142
Abstract

Magnetic resonance imaging (MRI) has potential as an imaging technique in fetal anatomy. In this article are presented images obtained from mouse fetuses at 16 days of pregnancy by means of the ultraconductive MRI system (JEOL AIM270). When fetuses removed from the uterus were fixed with 10% neutral formalin, various organs including heart, liver, lungs and bones were clearly seen, and a clear outline was obtained of the fetal skin and subcutaneous tissue by varying the setting. The same specimens were able to be used for histological evaluation. This MRI system will allow wider application in fetal anatomy and provide additional information about the developing mouse fetus.

摘要

磁共振成像(MRI)作为一种用于胎儿解剖结构的成像技术具有潜力。本文展示了通过超导MRI系统(日本电子AIM270)获得的妊娠16天小鼠胎儿的图像。当从子宫中取出的胎儿用10%中性福尔马林固定后,包括心脏、肝脏、肺和骨骼在内的各种器官清晰可见,通过改变设置还能获得胎儿皮肤和皮下组织的清晰轮廓。相同的标本可用于组织学评估。这种MRI系统将在胎儿解剖学中得到更广泛的应用,并为发育中的小鼠胎儿提供更多信息。

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