Maciunas R J, Berger M S, Copeland B, Mayberg M R, Selker R, Allen G S
Department of Neurological Surgery, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Neurosurg Clin N Am. 1996 Apr;7(2):245-66.
Interactive image-guided neurosurgical techniques allow safer and more complete cytoreduction of gliomas. This is most significant for low-grade tumors, whose configurations and margins are perhaps better appreciated by reference to registered MR images rather than by reliance on direct visualization using microscopic illumination. Spatially registered electro-physiologic recordings of intraoperative cortical stimulation to map language and motor function can increase the margin of safety for performing radical resections. By individualizing approaches and optimizing results, these technologies promise a new degree of standardization of outcome after resective surgery for all glial tumors.
交互式图像引导神经外科技术可实现更安全、更彻底的胶质瘤细胞减灭。这对于低级别肿瘤尤为重要，相较于依靠显微镜照明直接观察，参考配准的磁共振图像或许能更好地了解其形态和边界。术中对皮质进行刺激以绘制语言和运动功能图谱的空间配准电生理记录，可提高进行根治性切除手术的安全边际。通过个性化治疗方案并优化治疗效果，这些技术有望为所有胶质细胞瘤切除术后的预后带来新的标准化程度。
