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[抑郁症患者感觉运动节律的反应性]

[The reactivity of the sensorimotor rhythm in patients with depressive disorders].

作者信息

Viatleva O A, Puchinskaia L M, Gorobets L N

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1996 Mar-Apr;46(2):267-73.

PMID:8726559
Abstract

Reactions of mu-rhythm to sound (unspecific reactivity), actual and imaged movement (specific reactivity) were studied in 30 right-handed patients with psychogenic (Pg) and endogenous (Eg, cyclophrenia and low-progredient schizophrenia) subdepressive disorders and 23 healthy subjects. Predominant derangement of specific reactivity was revealed in patients which consisted in attenuation of reactions and reorganization of interhemispheric relations. During the actual movement there was a decrease in mu-rhythm reactivity in the left hemisphere and its increase in the right one. The imaged movement was associated with some decrease in the right-hemisphere mu-rhythm reactivity. The degree of reorganization of interhemispheric relations was higher in Eg patients, especially in schizophrenic ones. Abnormal ipsilateral reactions were induced by the actual (in Eg patients) or imaged movement (in Pg patients) with the right hand. These abnormal reactions are regarded as a return to an immature (childish) form. Only in schizophrenic patients the level of unspecific reactivity is lower than in the healthy subjects. There were no hemispheric differences in the sound-induced mu-rhythm reaction both in patients and healthy subjects.

摘要

对30名患有心因性(Pg)和内源性(Eg,环性精神病和低度进展性精神分裂症)亚抑郁障碍的右利手患者以及23名健康受试者,研究了μ节律对声音(非特异性反应性)、实际运动和想象运动(特异性反应性)的反应。结果显示,患者中特异性反应性存在主要紊乱,表现为反应减弱和半球间关系重组。在实际运动过程中,左半球μ节律反应性降低,右半球则升高。想象运动与右半球μ节律反应性的某种降低相关。Eg患者,尤其是精神分裂症患者,半球间关系重组程度更高。实际运动(在Eg患者中)或右手想象运动(在Pg患者中)会诱发异常的同侧反应。这些异常反应被视为回归到不成熟(幼稚)形式。仅在精神分裂症患者中,非特异性反应性水平低于健康受试者。患者和健康受试者在声音诱发的μ节律反应中均未出现半球差异。

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