Tajima S, Suzuki Y, Inazumi T, Mori N
Department of Dermatology, Keio University School of Medicine, Tokyo, Japan.
Dermatology. 1996;192(3):271-3. doi: 10.1159/000246383.
Systemic scleroderma is a disorder of unknown etiology with skin sclerosis. Its major histological features are swollen and homogenized collagen bundles.
We describe 2 patients with systemic sclerosis who have multiple umbilicated nodules indistinguishable from calcinosis cutis.
Histological examinations including Von Kossa staining revealed features of perforating granuloma annulare, but not of calcinosis cutis.
The association may not be fortuitous but both diseases may be etiologically related.
系统性硬化症是一种病因不明的伴有皮肤硬化的疾病。其主要组织学特征是胶原束肿胀和均质化。
我们描述了2例系统性硬化症患者，他们有多个与皮肤钙化症难以区分的脐状结节。
包括冯·科萨染色在内的组织学检查显示为穿通性环状肉芽肿的特征，而非皮肤钙化症的特征。
这种关联可能并非偶然，两种疾病在病因上可能相关。
