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爱泼斯坦-巴尔病毒和B细胞:仅此而已。

Epstein-Barr virus and the B cell: that's all it takes.

作者信息

Thorley-Lawson D A, Miyashita E M, Khan G

机构信息

Dept of Pathology, Tufts University School of Medicine, Boston, MA 02111, USA.

出版信息

Trends Microbiol. 1996 May;4(5):204-8. doi: 10.1016/s0966-842x(96)90020-7.

Abstract

Recent experiments demonstrate that a much broader range of B cells harbor Epstein-Barr virus (EBV) in vivo than was previously expected from in vitro studies. In this review it is argued that EBV persists in vivo by integrating its biology with that of the normal B cells within which it resides, and that the B cell provides all the environments necessary for EBV to maintain its life cycle.

摘要

最近的实验表明,体内携带爱泼斯坦-巴尔病毒(EBV)的B细胞范围比之前体外研究所预期的要广泛得多。在这篇综述中,有人认为EBV通过将自身生物学特性与所驻留的正常B细胞的生物学特性相结合而在体内持续存在,并且B细胞提供了EBV维持其生命周期所需的所有环境。

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