干扰素
The interferons.
作者信息
Skalla K
机构信息
Dartmouth Hitchcock Medical Center, Lebanon, NH, USA.
出版信息
Semin Oncol Nurs. 1996 May;12(2):97-105. doi: 10.1016/s0749-2081(96)80004-0.
OBJECTIVE
To provide a review of the biology, pharmacology, clinical application, and toxic effects of interferon and strategies for nursing management.
DATA SOURCES
Research studies, review articles, and book chapters pertaining to interferons.
CONCLUSIONS
Interferons are active therapeutic agents for hairy cell leukemia, chronic myelogenous leukemia, melanoma, and acquired immunodeficiency syndrome-related Kaposi's sarcoma. Clinical trials continue to investigate the clinical application of interferons.
IMPLICATIONS FOR NURSING PRACTICE
Oncology nurses can facilitate patient self-care in managing side effects of interferon therapy, provide patient and family education, and assist with reimbursement concerns.
目的
综述干扰素的生物学、药理学、临床应用、毒性作用及护理管理策略。
资料来源
有关干扰素的研究性文章、综述及书籍章节。
结论
干扰素是治疗毛细胞白血病、慢性粒细胞白血病、黑色素瘤及获得性免疫缺陷综合征相关卡波西肉瘤的有效治疗药物。临床试验仍在继续研究干扰素的临床应用。
对护理实践的启示
肿瘤专科护士可在干扰素治疗副作用管理方面促进患者自我护理，提供患者及家属教育，并协助解决报销问题。
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