Burkart J M
Bowman Gray School of Medicine, Winston-Salem, North Carolina 27157-1053, USA.
Perit Dial Int. 1996;16 Suppl 1:S340-6.
Catheter infections are a major cause of morbidity, catheter loss, and transfer to hemodialysis. These infections are mainly due to S. aureus. To date, treatment is less than optimal. Therefore, the primary goal should be prevention of catheter infections. Prevention is based on improving catheter design and implantation technique while using careful exit-site care. Prophylaxis with antimicrobials such as intranasal mupirocin or the use of silver-impregnated catheters appears promising as a way to reduce the risk of developing S. aureus infections. To optimize patient outcome, one must focus on these preventive measures.
导管感染是发病、导管丢失及转为血液透析的主要原因。这些感染主要由金黄色葡萄球菌引起。迄今为止，治疗效果欠佳。因此，首要目标应是预防导管感染。预防措施包括改进导管设计和植入技术，同时仔细做好出口部位护理。使用如鼻内莫匹罗星等抗菌药物进行预防或使用含银导管，作为降低金黄色葡萄球菌感染风险的一种方法似乎很有前景。为优化患者预后，必须关注这些预防措施。
