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美他利酮(ICI化合物33828)对鲇鱼(Heteropneustes fossilis (Bloch))卵巢活动的影响。

Effect of methallibure (ICI compound, 33, 828) on ovarian activity in the catfish, Heteropneustes fossilis (Bloch).

作者信息

Raizada R B, Singh T P

出版信息

Endocrinol Jpn. 1977 Apr;24(2):219-22. doi: 10.1507/endocrj1954.24.219.

Abstract

The effect of methallibure on ovary of H. fossilis was studied. Intraperitoneal administration of methalibure (100 microgram/g body weight) once a week for 4 weeks was very effective in suppressing the gametogenic and endocrine activities of ovary. The regressed condition of ovary was also apparent in GSI (2.84 to 1.09) readings. This decreased state of activity was further confirmed by reduced ovarian 32P uptake (28.00 to 18.10). The results obtained after the administration of the above compound on ovary were similar to those of surgical hypophysectomy.

摘要

研究了甲地孕酮对黄颡鱼卵巢的影响。每周一次腹腔注射甲地孕酮(100微克/克体重),持续4周,对抑制卵巢的配子发生和内分泌活动非常有效。卵巢的退化状况在性腺指数(GSI)读数(从2.84降至1.09)中也很明显。卵巢32P摄取量的减少(从28.00降至18.10)进一步证实了这种活性降低的状态。对卵巢施用上述化合物后获得的结果与手术切除垂体后的结果相似。

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