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[肠炎沙门氏菌所致腹主动脉瘤的长期发热综合征与感染]

[-Prolonged fever syndrome and infection of abdominal aortic aneurysm due to Salmonella enteritidis].

作者信息

Winkel M, Kufert A, Kaufman S, Giorcelli L, Carrillo J, Massone C

机构信息

Hospital Juan A. Fernadez, Buenos Aires, Argentina.

出版信息

Medicina (B Aires). 1995;55(4):341-4.

PMID:8728876
Abstract

Endovascular infection of atherosclerotic aorta is a rare event in the setting of aged patients with gram negative bacteremia of the salmonella group. Until the beginning of the 60s this meant an ominous diagnosis with an almost unavoidable fatal prognosis. Presently, this trend has been reverted, mostly due to an earlier diagnosis, the development of more sophisticated imaging techniques, the correct use of broad spectrum bactericidal antibiotics and prompt surgical management. Paradoxically, the incidence of arterial infections has increased in recent years, specially in old people with atherosclerotic abdominal aortic aneurysms, in whom infective endocarditis could not be demonstrated. We describe the case of a 65 year old man, with a history of longstanding non-insulin-dependent diabetes, presenting with protracted fever, weight loss and thigh pain. Blood cultures and serologic studies as well as several echocardiograms yielded negative results. An abdominal CT scan showed an infrarenal aortic aneurysm raising the clinical suspicion of arterial infection of abdominal aorta. The patient underwent surgery because of highly presumptive diagnosis of complicated aortic aneurysm. The resection was followed by an in situ graft. There was no evidence of disruption or gross collection. Samples of the aortic wall and perianeurysmatic fluid grew Salmonella enteritides. We describe the main etiopathogenic and clinic features of the entity highlighting the high sensitivity and specificity of the CT scan in the identification and characterization of infected aortic aneurysm. Certain features may firmly suggest this diagnosis without using preoperative aortography.

摘要

在患有沙门氏菌属革兰氏阴性菌血症的老年患者中,动脉粥样硬化性主动脉的血管内感染是一种罕见事件。直到60年代初,这意味着一种不祥的诊断,预后几乎不可避免地是致命的。目前,这种趋势已经逆转,主要是由于早期诊断、更先进成像技术的发展、广谱杀菌抗生素的正确使用以及及时的手术治疗。矛盾的是,近年来动脉感染的发生率有所增加,特别是在患有动脉粥样硬化性腹主动脉瘤的老年人中,这些患者无法证实存在感染性心内膜炎。我们描述了一名65岁男性的病例,他有长期非胰岛素依赖型糖尿病史,出现持续发热、体重减轻和大腿疼痛。血培养、血清学研究以及多次超声心动图检查结果均为阴性。腹部CT扫描显示肾下腹主动脉瘤,增加了腹主动脉动脉感染的临床怀疑。由于高度怀疑为复杂性主动脉瘤,患者接受了手术。切除术后进行原位移植。没有破裂或大量积液的证据。主动脉壁和动脉瘤周围液体样本培养出肠炎沙门氏菌。我们描述了该疾病的主要病因和临床特征,强调了CT扫描在识别和表征感染性主动脉瘤方面的高敏感性和特异性。某些特征可能在不进行术前主动脉造影的情况下就强烈提示该诊断。

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