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[妊娠毒血症病因学的免疫学方面]

[Immunologic aspects on the etiology of pregnancy toxemia].

作者信息

Buitron Garcia R G, Oropeza Rechy G, Bravo Gutierrez R, Villafuerte Canales J, Buitron Lopez F

机构信息

Hospital General de México SS.

出版信息

Ginecol Obstet Mex. 1996 Mar;64:131-4.

PMID:8729190
Abstract

Since 70 years ago, the possibility that the etiology of Gravidic Toxemia is inmunologic has been studied. Several researchers agree in the disminution of the levels of IgG with no modifications on the levels of complement fractions. The determination of IgA, IgM, IgC, C3 and C4 was made on fifteen pacients with gravidic toxemia and fifteen pacients that presented no complicated pregnancy. The results are the same as the reported facts like disminution of IgG, it was observed also, a disminution on the complement fractions C3 and C4. The research let us stabblish the posibility of a sikness caused by immune complexs having as an antigenic stimulations the trofoblast.

摘要

自70年前起,就开始研究妊娠中毒症病因是否为免疫性的可能性。几位研究人员一致认为IgG水平降低,而补体成分水平无变化。对15例妊娠中毒症患者和15例无妊娠并发症的患者进行了IgA、IgM、IgC、C3和C4的测定。结果与所报道的事实相同,即IgG降低,同时也观察到补体成分C3和C4降低。该研究使我们确定了一种由免疫复合物引起疾病的可能性,这种免疫复合物以滋养层作为抗原刺激物。

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