Davy J M, Pons M, Beck L, Ferrière M
Service de cardiologie B, hôpital Arnaud-de-Villeneuve, CHU de Montpellier.
Arch Mal Coeur Vaiss. 1995 Dec;88 Spec No 5:55-62.
New indications have recently appeared for cardiac pacing with haemodynamic and antiarrhythmic objectives without any symptomatic bradycardia. The best documented indication, though relatively rare, is stimulation of obstructive hypertrophic cardiomyopathy; initially reserved for cases with favorable results of an acute haemodynamic test, it is now used in other cases without this criterion; hypertrophic cardiomyopathy without permanent obstruction, atrial fibrillation or left bundle branch block. The improvement observed during follow-up is always greater as a real remodeling of the myocardium seems to occur with ventricular dilatation and/or septal thinning. However, the position of the atrial, and above all, of the ventricular pacing catheters is critical as is regulation of the pacemaker which should allow complete ventricular capture with an AV delay allowing good filling. The follow-up of these patients must therefore be regular and the effects on longevity are unknown. DDD pacing has also been proposed in dilated cardiomyopathy. The results are contradictory and only very selected cases with left bundle branch block and long PR interval seem justified with, again, optimisation of the pacing sites with high septal or biventricular stimulation. Recurrent atrial tachycardia, special algorithms preventing extrasystoles have been tried with variable results. In cases with inter-atrial block, atrial resynchronisation by bi-atrial stimulation has been assessed with promising results but many technical problems remain unsolved.
近期出现了一些心脏起搏的新适应证,其目的是改善血流动力学和抗心律失常,而患者并无任何症状性心动过缓。有充分文献记载的适应证,尽管相对少见,是用于刺激梗阻性肥厚型心肌病;最初仅用于急性血流动力学试验结果良好的病例,现在也用于不满足该标准的其他病例,如无永久性梗阻、心房颤动或左束支传导阻滞的肥厚型心肌病。随访期间观察到的改善总是更大,因为随着心室扩张和/或室间隔变薄,似乎真的发生了心肌重塑。然而,心房尤其是心室起搏导管的位置至关重要,起搏器的调节也很关键,应能实现完全心室夺获,并伴有允许良好充盈的房室延迟。因此,必须对这些患者进行定期随访,其对寿命的影响尚不清楚。DDD起搏也已被提议用于扩张型心肌病。结果相互矛盾,似乎只有非常特定的伴有左束支传导阻滞和长PR间期的病例才适用,同样需要通过高位间隔或双心室刺激来优化起搏部位。对于反复发生的房性心动过速,尝试了预防早搏的特殊算法,结果各异。在存在房间阻滞的病例中,通过双心房刺激进行心房再同步化已得到评估,结果很有前景,但许多技术问题仍未解决