Hoang-Xuan K, Delattre J Y
Clinique neurologique, Hôpital de la Salpêtrière, Paris.
Rev Prat. 1996 Feb 15;46(4):450-6.
Chemotherapy of primary malignant brain tumors (PMBT) is palliative, except for germinomas. It is used as adjuvant therapy or alone at recurrence. The chemosensitivity of PMBT differs among tumors of different histological types. The role of chemotherapy in the treatment strategy will be reviewed by tumor type (malignant astrocytic gliomas, anaplastic oligodendrogliomas and mixed gliomas, anaplastic ependymomas, medulloblastomas, germinomas, primary malignant cerebral lymphoma).
原发性恶性脑肿瘤(PMBT)的化疗是姑息性的,但生殖细胞瘤除外。它用作辅助治疗或在复发时单独使用。PMBT的化疗敏感性在不同组织学类型的肿瘤之间存在差异。将按肿瘤类型(恶性星形细胞胶质瘤、间变性少突胶质细胞瘤和混合性胶质瘤、间变性室管膜瘤、髓母细胞瘤、生殖细胞瘤、原发性恶性脑淋巴瘤)对化疗在治疗策略中的作用进行综述。