Low W K, Fong K W
Department of Otolaryngology, Singapore General Hospital.
J Laryngol Otol. 1996 Feb;110(2):121-3. doi: 10.1017/s0022215100132931.
This paper evaluates post-irradiation hearing changes in patients with nasopharyngeal carcinoma (NPC) from a disability orientated approach, which takes into account binaural hearing. Newly diagnosed patients with NPC were studied before radiotherapy, and at four to 12 months (mean 9.2 months) after radiotherapy, provided they remained disease-free. Each patient was examined clinically and with pure tone audiograms. Tympanometry was used to confirm middle ear effusion. Averaged hearing thresholds over 0.5, 1 and 2 kHz were evaluated. If abnormal (> 30 dB), the resultant hearing disability was illustrated by a modified Glasgow Plot. Twenty-three males and 10 females completed the study. Middle ear effusions resulted in 39.3 per cent (binaural in two patients) and 33.3 per cent (binaural in five patients) of patients having hearing disability pre- and post-irradiation respectively. No patient had hearing disability as a result of a sensorineural loss. It is recommended that future reporting of post-irradiation hearing changes in patients with NPC, as in middle ear surgery, be considered from a disability-orientated approach.
本文从残疾导向的角度评估了鼻咽癌（NPC）患者放疗后的听力变化，该方法考虑了双耳听力。对新诊断的NPC患者在放疗前以及放疗后4至12个月（平均9.2个月）进行研究，前提是他们仍无疾病。对每位患者进行临床检查和纯音听力图检查。使用鼓室图确认中耳积液。评估0.5、1和2kHz的平均听力阈值。如果异常（>30dB），则用改良的格拉斯哥图说明由此产生的听力残疾。23名男性和10名女性完成了该研究。中耳积液分别导致39.3%（两名患者双耳）和33.3%（五名患者双耳）的患者在放疗前和放疗后出现听力残疾。没有患者因感音神经性听力损失而出现听力残疾。建议未来在报告NPC患者放疗后的听力变化时，如同中耳手术一样，应从残疾导向的角度进行考虑。
