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[睁眼时有或无阻断的枕叶癫痫样活动:一项临床脑电图对比研究]

[Occipital epileptiform activity with or without blockade with eye opening: a comparative clinico-electroencephalographic study].

作者信息

Fonseca L C, Tedrus G M

机构信息

Departamento de Neuropsiquiatria, Pontifícia Universidade Católica de Campinas.

出版信息

Arq Neuropsiquiatr. 1995 Dec;53(4):724-9. doi: 10.1590/s0004-282x1995000500002.

DOI:10.1590/s0004-282x1995000500002
PMID:8729763
Abstract

Occipital epileptiform activity blocked by eyes opening (OEAB) is primarily observed in childhood epilepsy with occipital paroxysms but may be also found in cases of benign childhood epilepsy with centrotemporal spikes, cryptogenic/symptomatic partial epilepsies, idiopathic generalized epilepsies and in patients with no seizures. We studied comparatively EEG and clinical features of 20 patients with OEAB and 120 patients with occipital epileptiform activity not suppressed by eyes opening (OEA). Epileptiform activity (OEA or OEAB) was registered until the 7 years of age in 67.5% of the patients with OEA and in 45% of the patients with OEAB. Epileptic seizures began before 4 years of age in 44.4% of the cases with OEA and in 14.2% in the group OEAB. Febrile convulsions alone occurred only in the OEA group (12.5%). Developmental retardation was referred in 27 patients with OEP. The occurrence of spike and wave complexes was statistically more frequent among patients with OEAB (80.0%) as opposed to patients with OEA (17.5%). Our findings suggest clinical and electroencephalographic differences between children with OEA and OEAB.

摘要

睁眼阻断枕叶癫痫样活动(OEAB)主要见于伴有枕叶阵发的儿童癫痫,但在伴有中央颞区棘波的良性儿童癫痫、隐源性/症状性部分性癫痫、特发性全身性癫痫以及无癫痫发作的患者中也可能出现。我们比较研究了20例OEAB患者和120例睁眼未抑制枕叶癫痫样活动(OEA)患者的脑电图及临床特征。67.5%的OEA患者和45%的OEAB患者在7岁之前记录到癫痫样活动(OEA或OEAB)。44.4%的OEA病例和14.2%的OEAB组病例癫痫发作始于4岁之前。仅热性惊厥仅发生在OEA组(12.5%)。27例OEP患者存在发育迟缓。与OEA患者(17.5%)相比,棘慢复合波在OEAB患者中出现的统计学频率更高(80.0%)。我们的研究结果提示OEA和OEAB儿童在临床和脑电图方面存在差异。

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