Suh T S, Bova F J, Yoon S C, Choe B Y, Kim M C, Shinn K S, Bahk Y W, Ha S W, Park C I
Department of Radiology, Kang-nam St Mary's Hospital, Catholic University Medical College, Seoul, Republic of Korea.
Phys Med Biol. 1996 Apr;41(4):675-96. doi: 10.1088/0031-9155/41/4/007.
In order to efficiently plan non-spherical radiosurgical targets we have used computer-aided design optimization techniques with a fast dose model. A study of the spatial dose distribution for single or multiple non-coplanar arcs was carried out using a 18 cm diameter spherical head model. The dose distribution generated from the 3D dose computation algorithm can be represented by a simple analytic form. Two analytic dose models were developed to represent the dose for preset multiple non-coplanar arcs or a single arc: spherical and cylindrical. The spherical and cylindrical dose models compute dose quickly for each isocentre and single arc. Our approach then utilizes a computer-aided design optimization (CAD) with the use of two fast approximate dose models to determine the positions of isocentres and arcs. The implementation of CAD with fast dose models was demonstrated. While the fast dose models are only approximations of the true dose distribution, it is shown that this approximate model is sufficient to optimize isocentric position, collimator size and arc positions with CAD.
为了有效地规划非球形放射外科手术靶点，我们使用了计算机辅助设计优化技术和快速剂量模型。使用直径为18 cm的球形头部模型对单条或多条非共面弧的空间剂量分布进行了研究。三维剂量计算算法生成的剂量分布可以用一种简单的解析形式表示。开发了两种解析剂量模型来表示预设的多条非共面弧或单条弧的剂量：球形和圆柱形。球形和圆柱形剂量模型能为每个等中心和单条弧快速计算剂量。然后，我们的方法利用计算机辅助设计优化（CAD）以及两个快速近似剂量模型来确定等中心和弧的位置。展示了使用快速剂量模型的CAD实现。虽然快速剂量模型只是真实剂量分布的近似，但结果表明，这种近似模型足以通过CAD优化等中心位置、准直器尺寸和弧的位置。
