胰岛素对血管对去甲肾上腺素反应性的影响。
The effect of insulin on vascular reactivity to norepinephrine.
作者信息
Alexander W D, Oake R J
出版信息
Diabetes. 1977 Jul;26(7):611-4. doi: 10.2337/diab.26.7.611.
PMID:873069
Abstract
The effect of insulin on the vasoconstrictor response to norepinephrine of the resistance bed of the isolated perfused rat tail has been studied. Insulin produced a significant attenuation of this response in concentrations of both 120 mU./ml. and 150 micronU./ml. It is suggested that this effect may be relevant to the hypotensive action of insulin observed in diabetics.
摘要
研究了胰岛素对离体灌注大鼠尾部阻力血管床去甲肾上腺素血管收缩反应的影响。胰岛素在浓度为120 mU/ml和150 μU/ml时，均能显著减弱这种反应。提示该效应可能与糖尿病患者中观察到的胰岛素降压作用有关。
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