Garfinkel P E, Lin E, Goering P, Spegg C, Goldbloom D, Kennedy S, Kaplan A S, Woodside D B
Health Systems Research Unit, Clarke Institute of Psychiatry, University of Toronto, Toronto Ontario, Canada.
Br J Psychiatry. 1996 Apr;168(4):500-6. doi: 10.1192/bjp.168.4.500.
This study compares the characteristics of women with anorexia nervosa with those of women who have all the diagnostic features of that disorder except amenorrhoea.
The study uses data from a large community epidemiological survey of the mental health status of household residents in Ontario, Canada. A multi-stage stratified sampling design generated a sample of 4285 females aged 15-64. DSM-III-R diagnoses were made using the Composite International Diagnostic interview.
Eighty-four out of 4285 female respondents met full or partial-syndrome criteria for anorexia nervosa. Comparison of these two groups revealed few statistically significant differences in terms of demographics, psychiatric comorbidity, family history or early experiences.
Amenorrhoea did not discriminate between women with anorexia nervosa and women with all the features except amenorrhoea across a number of relevant variables. The authors question the utility of amenorrhoea as a diagnostic criterion.
本研究比较了神经性厌食症女性与具有该疾病除闭经外所有诊断特征的女性的特点。
该研究使用了来自加拿大安大略省家庭居民心理健康状况大型社区流行病学调查的数据。多阶段分层抽样设计产生了一个由4285名15 - 64岁女性组成的样本。使用综合国际诊断访谈进行DSM - III - R诊断。
4285名女性受访者中有84人符合神经性厌食症的全部或部分综合征标准。这两组的比较显示，在人口统计学、精神疾病共病、家族史或早期经历方面，几乎没有统计学上的显著差异。
在一些相关变量上，闭经并不能区分神经性厌食症女性和具有除闭经外所有特征的女性。作者质疑闭经作为诊断标准的效用。
