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[精氨酸与一氧化氮的心血管效应]

[Cardiovascular effects of arginine and nitric oxide].

作者信息

Faintuch J, Faintuch J J

机构信息

Faculdade de Medicina da U.S.P.

出版信息

Rev Hosp Clin Fac Med Sao Paulo. 1995 Nov-Dec;50(6):334-8.

PMID:8731256
Abstract

Amino acids are an unusual chemical category because they are endowed with alimentary properties, but at the same time they may determine typical pharmacologic responses in some circumstances. These facts were responsible for the origin of modern pharmaconutrition, which has been using arginine for some time because of its beneficial impact on immune function, nitrogen anabolism and wound healing. The recent identification of its metabolite NO (nitric oxide), a powerful mediator related to a large number of physiologic and pathophysiologic phenomenons, has augmented the interest for this amino acid.

摘要

氨基酸是一类特殊的化学物质,因为它们具有营养特性,但同时在某些情况下也可能引发典型的药理反应。这些事实促成了现代药物营养的诞生,由于精氨酸对免疫功能、氮合成代谢和伤口愈合具有有益影响,药物营养领域使用精氨酸已有一段时间。最近发现其代谢产物一氧化氮(NO)是一种与大量生理和病理生理现象相关的强效介质,这进一步增加了人们对这种氨基酸的兴趣。

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