Lin C, Zhu X, Chai Z
Shanghai Sixth People's Hospital.
Zhonghua Wai Ke Za Zhi. 1995 Sep;33(9):548-50.
From 1975 to 1989, we treated 238 cases of gastric carcinoma in III stage, 90.7% of these were followed up. The total 5-year survival rate was 45.4%, 10-year survival 33.7%. The 5-year survival rate and 10-year survival rate (56.3% and 47.5%) in the extensive radical treatment group (102 cases, selective R3 or R3) was much higher than that of routine radical treatment group (114 cases R2). The 5-year survival rate and 10-year survival rate in the group with auxillary post-operational chemotherapy were much higher than those of the group without chemotherapy. The post-operative survival rate in the group with chemotherapy plus Chinese medicine was much higher than that of the group with chemotherapy alone. The peritoneal metastatic rate of the group with peritoneal flushing plus chemotherapy (18.7% and 20.6%) was much longer than that of the group without peritoneal flushing and/or chemotherapy (31.9%). We consider that the best treatment of gastric carcinoma in III stage is the sufficient removal of gastric lymph nodes for the prevention of metastasis through peritoneal and circulatory route.
1975年至1989年，我们治疗了238例III期胃癌患者，其中90.7%进行了随访。5年总生存率为45.4%，10年生存率为33.7%。扩大根治术组（102例，选择性R3或R3）的5年生存率和10年生存率（56.3%和47.5%）远高于常规根治术组（114例，R2）。术后辅助化疗组的5年生存率和10年生存率远高于未化疗组。化疗加中药组的术后生存率远高于单纯化疗组。腹腔冲洗加化疗组的腹腔转移率（18.7%和20.6%）远低于未进行腹腔冲洗和/或化疗组（31.9%）。我们认为，III期胃癌的最佳治疗方法是充分清除胃淋巴结，以预防通过腹膜和循环途径的转移。
