Edge J A
Department of Paediatrics, John Radcliffe Hospital, University of Oxford.
Br J Hosp Med. 1996;55(8):508-12.
Diabetic ketoacidosis remains a life-threatening condition. Management is usually straightforward, but there is still a significant mortality and morbidity, largely arising from the unpredictable complication of cerebral oedema. The pathophysiology of this devastating condition is still unknown. Good supervision from senior members of staff is essential, and there should be early concern if progress is not as predicted. Rapid intervention with mannitol and hyperventilation is necessary if signs of cerebral oedema develop.
糖尿病酮症酸中毒仍然是一种危及生命的病症。治疗通常较为直接，但仍存在显著的死亡率和发病率，主要源于难以预测的脑水肿并发症。这种灾难性病症的病理生理学仍不清楚。资深工作人员的良好监督至关重要，如果病情进展未如预期，应尽早予以关注。如果出现脑水肿迹象，必须迅速用甘露醇进行干预并实施过度通气。
