Bristow M F, Kohen D
Cheam Resource Centre, St Helier Trust University Hospital, Surrey.
Br J Hosp Med. 1996;55(8):517-20.
Neuroleptic malignant syndrome is a rare, idiosyncratic condition related to neuroleptic use which may develop at any stage during neuroleptic treatment and can prove fatal. Although most commonly seen in psychiatric patients, anyone prescribed a neuroleptic is at risk and it has been associated with other agents. This article discusses its recognition, risk factors, clinical course and treatment, together with a summary of current thinking on its aetiology.
抗精神病药物恶性综合征是一种与使用抗精神病药物相关的罕见的特异反应性疾病,可在抗精神病药物治疗的任何阶段发生,且可能致命。虽然最常见于精神科患者,但任何服用抗精神病药物的人都有风险,并且它还与其他药物有关。本文讨论了其识别、危险因素、临床过程和治疗方法,以及对其病因的当前认识总结。