Tribouilloy C, Shen W F, Leborgne L, Trojette F, Rey J L, Lesbre J P
Department of Cardiology, South Hospital, University of Picardie, Amiens, France.
Eur Heart J. 1996 Feb;17(2):272-80. doi: 10.1093/oxfordjournals.eurheartj.a014845.
The purpose of this study was to examine the value of non-invasive clinical and Doppler echocardiographic findings, compared to cardiac catheterization, in management decision-making for patients with left-sided valvular regurgitation.
One hundred and thirty-five consecutive patients with left-sided valvular regurgitation who underwent cardiac catheterization and detailed Doppler echocardiography were prospectively studied. Two independent groups of experienced cardiologists, given clinical information combined with either Doppler echocardiographic or cardiac catheterization data, decided to operate, not to operate, or remained uncertain.
In 63 (81%) of 78 patients with mitral regurgitation, there was agreement on the decision for valve surgery or medical treatment between Doppler echocardiography and cardiac catheterization. Valve repair was performed in 22 patients, which agreed with the echocardiographic decision. In the remaining 15 patients, although the severity and type of mitral valve lesions and left ventricular functional status were confirmed by Doppler echocardiography, the clinical decision was uncertain; additional information concerning coronary anatomy (13 patients) and pulmonary artery pressure (one patient) or both (one patient) was required. In 47 of 57 patients (82%) with aortic regurgitation, there was agreement on their management as a result of Doppler echocardiography and cardiac catheterization findings. In 10 patients, the clinical decision reached with the help of Doppler echocardiography alone was uncertain and coronary (seven patients), left ventricular (two patients) angiography or aortography (one patient) were requested. Overall, there were no conflicting clinical decisions made by the two methods in patients with either mitral or aortic regurgitation.
In every patient in whom it was considered that a decision could be reached by echocardiography alone (more than 80% of patients) there was 100% agreement from the cardiac catheterization assessment group on the management decision. Therefore, in patients with significant mitral or aortic regurgitation where echocardiographic data is adequate, cardiac catheterization can be safely omitted from the investigative process for surgery. Where echocardiographic indices are conflicting, or significant coronary artery disease is suspected, cardiac catheterization is required.
本研究旨在探讨与心导管检查相比,无创临床及多普勒超声心动图检查结果在左侧瓣膜反流患者治疗决策中的价值。
前瞻性研究了135例连续接受心导管检查及详细多普勒超声心动图检查的左侧瓣膜反流患者。两组独立的经验丰富的心脏病专家,分别根据临床信息结合多普勒超声心动图或心导管检查数据,决定是否手术、不手术或仍不确定。
在78例二尖瓣反流患者中的63例(81%),多普勒超声心动图与心导管检查在瓣膜手术或药物治疗决策上达成一致。22例患者接受了瓣膜修复,这与超声心动图的决策一致。在其余15例患者中,尽管多普勒超声心动图证实了二尖瓣病变的严重程度和类型以及左心室功能状态,但临床决策仍不确定;需要有关冠状动脉解剖结构(13例患者)和肺动脉压力(1例患者)或两者(1例患者)的额外信息。在57例主动脉瓣反流患者中的47例(82%),根据多普勒超声心动图和心导管检查结果在治疗决策上达成一致。在10例患者中,仅依靠多普勒超声心动图做出的临床决策不确定,需要进行冠状动脉(7例患者)、左心室(2例患者)血管造影或主动脉造影(1例患者)检查。总体而言,二尖瓣或主动脉瓣反流患者中两种方法未做出相互矛盾的临床决策。
在每例被认为仅通过超声心动图即可做出决策的患者(超过80%的患者)中,心导管检查评估组在治疗决策上与之一致率达100%。因此,对于有明显二尖瓣或主动脉瓣反流且超声心动图数据充分的患者,手术检查过程中可安全省略心导管检查。当超声心动图指标相互矛盾或怀疑有严重冠状动脉疾病时,则需要进行心导管检查。