Carson H J, Candel A G, Gattuso P, Castelli M J
Department of Pathology, Loyola University Medical Center, Maywood, IL USA.
Diagn Cytopathol. 1996 May;14(3):216-20. doi: 10.1002/(SICI)1097-0339(199604)14:3<216::AID-DC4>3.0.CO;2-F.
Malignancies from many primary sites may metastasize to supraclavicular lymph nodes (SCLN). We reviewed 100 fine-needle aspirations (FNAs) of SCLNs. There were three major types of malignancy detected by this method: adenocarcinoma (n = 40), squamous cell carcinoma (n = 14), and other malignancies (n = 29). Adenocarcinomas and other malignancies from all sites tended to metastasize to the left SCLN. Squamous cell carcinomas from all sites, however, tended to appear on the right side. For 61 patients, a previous diagnosis of malignancy had been made within 1 yr of the clinical appearance of the abnormal SCLN. For 20 patients, the primary diagnosis antedated SCLN metastasis by more than 1 yr, particularly patients with adenocarcinoma of the breast, prostate, or thyroid papillary carcinoma.
许多原发部位的恶性肿瘤可能会转移至锁骨上淋巴结（SCLN）。我们回顾了100例SCLN的细针穿刺抽吸活检（FNA）。通过该方法检测到三种主要类型的恶性肿瘤：腺癌（n = 40）、鳞状细胞癌（n = 14）和其他恶性肿瘤（n = 29）。所有部位的腺癌和其他恶性肿瘤倾向于转移至左侧SCLN。然而，所有部位的鳞状细胞癌倾向于出现在右侧。61例患者在异常SCLN临床表现出现的1年内曾被诊断为恶性肿瘤。20例患者的原发诊断早于SCLN转移超过1年，尤其是患有乳腺癌、前列腺癌或甲状腺乳头状癌的患者。
