Rocskay A Z, Harbut M R, Green M A, Osher D L, Zellers E T
Center for Occupational and Environmental Medicine, Southfield, Michigan, USA.
Am J Ind Med. 1996 May;29(5):459-66. doi: 10.1002/(SICI)1097-0274(199605)29:5<459::AID-AJIM4>3.0.CO;2-H.
This study aimed to determine the prevalence of respiratory morbidity among asbestos-exposed ironworkers and to determine the relationship between respiratory morbidity indices and length of exposure. A medical screening provided information on chest radiographic abnormalities, pulmonary function, rales, finger clubbing, and respiratory symptoms for 547 asbestos-exposed ironworkers. Union pension records furnished data on length of exposure. The study group exhibited on increased prevalence of small irregular opacities, pleural plaques, and pleural thickening on chest x-ray; reduced FEF 25-75; rales; and respiratory symptoms. After controlling for the effect of cigarette smoking and age, years since joining the ironworkers union were significantly associated with profusion, pleural thickening, pleural plaques, rales, percent predicted FVC, reduced FVC, reduced FEV1, reduced FEV1/FVC, and dyspnea grades I, II, III, and IV.
本研究旨在确定接触石棉的钢铁工人中呼吸系统疾病的患病率,并确定呼吸系统疾病指标与接触时长之间的关系。一项医学筛查提供了547名接触石棉的钢铁工人的胸部X光异常、肺功能、啰音、杵状指和呼吸道症状等信息。工会养老金记录提供了接触时长的数据。研究组胸部X光显示小的不规则阴影、胸膜斑和胸膜增厚的患病率增加;用力呼气流量25%-75%降低;有啰音;以及有呼吸道症状。在控制了吸烟和年龄的影响后,自加入钢铁工人工会以来的年数与小阴影密集度、胸膜增厚、胸膜斑、啰音、预计用力肺活量百分比、用力肺活量降低、第一秒用力呼气容积降低、第一秒用力呼气容积/用力肺活量降低以及I、II、III和IV级呼吸困难显著相关。