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[白蛋白梯度在不同病因腹水诊断中的效能]

[Diagnostic efficacy of albumin gradient in different causes of ascitis].

作者信息

Laudanno O M, Bresciani P, Silva M

机构信息

Hospital de Clínicas, José de San Martín, UBA.

出版信息

Acta Gastroenterol Latinoam. 1995;25(5):285-90.

PMID:8733254
Abstract

The aim of this study was to compare the serum-ascites albumin gradient (GS-A) to the transudate-exudate concept in the classification of ascites. The second objective was to analyze the predictive value and efficacy of GS-A, ascites total protein, LDH, Ratio and ascites cholesterol in patients with liver disease and malignant ascites. For this purpose we studied prospectively 98 patients (in prospective form). The transudate-exudate concept classified correctly the causes of ascites only in 65.6% of the patients. In contrast, the GS-A did it 95.7% of the patients. In differentiating ascites caused either by chronic liver disease or by malignancy, the tests with best efficacy were cholesterol (98%), (predictive value 97%) and GS-A efficacy 94% (predictive value 94%). We conclude that GS-A was better than the traditional transudate-exudate concept in classification of ascites. The test with the best efficcacy separating ascites caused by chronic liver disease or by malignancy was the ascites cholesterol.

摘要

本研究的目的是在腹水分类中比较血清腹水白蛋白梯度(GS-A)与漏出液-渗出液概念。第二个目标是分析GS-A、腹水总蛋白、乳酸脱氢酶、比率及腹水胆固醇对肝病和恶性腹水患者的预测价值及效能。为此,我们前瞻性地研究了98例患者(以前瞻性方式)。漏出液-渗出液概念仅在65.6%的患者中正确分类了腹水原因。相比之下,GS-A在95.7%的患者中做到了这一点。在区分由慢性肝病或恶性肿瘤引起的腹水时,效能最佳的检测是胆固醇(98%),(预测价值97%)和GS-A效能94%(预测价值94%)。我们得出结论,在腹水分类中,GS-A优于传统的漏出液-渗出液概念。区分由慢性肝病或恶性肿瘤引起的腹水的效能最佳的检测是腹水胆固醇。

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