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与巨细胞病毒相关的蛋白丢失性胃病:异基因骨髓移植的一种罕见且晚期并发症。

Protein-losing gastropathy associated with cytomegalovirus: a rare and late complication of allogeneic bone marrow transplantation.

作者信息

Pinho Vaz C, Ibrahim A, Avila Garavito A, Vantelon J M, Bourhis J H, Charnoze I, Buffet C, Pico J L

机构信息

Bone Marrow Transplantation Unit, Institut Gustave Roussy, Villejuif, France.

出版信息

Bone Marrow Transplant. 1996 May;17(5):887-9.

PMID:8733717
Abstract

A 36-year-old women with chronic myelogenous leukemia in first chronic phase received a bone marrow transplant from her HLA-identical brother. The preparatory regimen consisted of total body irradiation (10 Gy) and cyclophosphamide (60 mg/kg for 2 days). Full engraftment was achieved and the woman was monitored as an outpatient after discharge from hospital on day 35. One year after BMT, while she was on cyclosporin A and steroids because of chronic graft-versus-host disease, the patient developed protein-losing gastropathy associated with cytomegalovirus infection (with no gastrointestinal symptoms), which regressed spontaneously in 4 weeks.

摘要

一名处于慢性期的36岁慢性粒细胞白血病女性患者接受了来自其HLA配型相同的兄弟的骨髓移植。预处理方案包括全身照射(10戈瑞)和环磷酰胺(60毫克/千克,连用2天)。实现了完全植入,该女性在第35天出院后作为门诊患者接受监测。骨髓移植一年后,由于慢性移植物抗宿主病,她正在接受环孢素A和类固醇治疗,此时患者出现了与巨细胞病毒感染相关的蛋白丢失性胃病(无胃肠道症状),4周后自行消退。

相似文献

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Protein-losing gastropathy associated with cytomegalovirus: a rare and late complication of allogeneic bone marrow transplantation.与巨细胞病毒相关的蛋白丢失性胃病:异基因骨髓移植的一种罕见且晚期并发症。
Bone Marrow Transplant. 1996 May;17(5):887-9.
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引用本文的文献

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Simultaneous occurrence of gastric antral vascular ectasia and protein-losing enteropathy in chronic graft-versus-host disease.慢性移植物抗宿主病中同时发生的胃窦血管扩张症和蛋白丢失性肠病。
Int J Hematol. 2013 Apr;97(4):529-34. doi: 10.1007/s12185-013-1279-y. Epub 2013 Feb 3.
2
Cytomegalovirus-associated protein-losing gastropathy in childhood.儿童巨细胞病毒相关蛋白丢失性胃病
Eur J Pediatr. 2008 Nov;167(11):1217-20. doi: 10.1007/s00431-008-0791-1. Epub 2008 Jul 24.