Prévot M, Renier D, Marchac D
Unité de Chirurgie Craniofaciale, Hôpital Necker-Enfants-Malades, Paris.
Ann Chir Plast Esthet. 1996 Feb;41(1):45-57.
The Center for Craniofacial Anomalies of Necker-Enfants-Malades Hospital presents a retrospective study of the outcome of 592 patients who were operated for craniosynostosis between 1976 and 1991. The quality of ossification one year after operation is reported with a focus on influencing factors. The lack of ossification rate is 5% (30/592). Three parameters are identified as increasing the risk of poor osseous wound healing: local postoperative infection, forehead advancement especially when accomplished with resorbable osteosynthesis, and brachycephaly. On the contrary, repaired tears of the dura mater do not seem to pose a risk. Seventy five per cent of patients with local infection and 12.4% of forehead advancement presented a lack of ossification which is statistically significant (p < 0.001). Lack of ossification can compromise aesthetic and functional results. Decreasing postoperative infection and stable fixation may help to avoid it.
内克尔儿童医院颅面畸形中心对1976年至1991年间接受颅缝早闭手术的592例患者的手术结果进行了一项回顾性研究。报告了术后一年的骨化质量，并重点关注影响因素。骨化缺失率为5%（30/592）。确定了三个增加骨伤口愈合不良风险的参数：局部术后感染、前额前移（尤其是采用可吸收骨合成材料进行前额前移时）和短头畸形。相反，硬脑膜修补撕裂似乎不会带来风险。75%的局部感染患者和12.4%的前额前移患者出现骨化缺失，具有统计学意义（p<0.001）。骨化缺失会影响美观和功能结果。减少术后感染和稳定固定可能有助于避免这种情况。
