Haouet H, Ben Hamida A, Haouet S, Chaffai M, Ben Osman A
Service de Dermatologie, Hôpital La Rabta, Tunis.
Ann Dermatol Venereol. 1996;123(1):9-11.
Pemphigus frequently seen in Tunisia has specific characteristics distinguishing it from the European or American forms. Between 1974 and 1992, we observed 70 cases in the dermatology unit of the La Rabta University Hospital in Tunis. Most patients were young (mean age 39 yr), predominantly women (80%). Deep pemphigus (pemphigus vulgaris and vegetans) occurred in 56% and superficial pemphigus (seborrheic and foliaceus) in 44%. High-dose corticosteroids were given as initial treatment (1.4 mg/kg/day). Infectious complications were frequent. Mortality was 14%. Pemphigus in Europe and North America usually occurs in adults in the 50-60 year age range. Superficial forms are rare (2-10%). In Tunisia, pemphigus is similar to Brazilian pemphigus with high frequency and predominant superficial forms (pemphigus foliaceus).
在突尼斯常见的天疱疮具有一些特定特征,使其有别于欧洲或美国的类型。1974年至1992年间,我们在突尼斯拉巴塔大学医院皮肤科观察到70例病例。大多数患者较为年轻(平均年龄39岁),以女性为主(80%)。深部天疱疮(寻常型天疱疮和增殖型天疱疮)占56%,浅表性天疱疮(脂溢性和落叶型)占44%。初始治疗采用大剂量皮质类固醇(1.4毫克/千克/天)。感染性并发症很常见。死亡率为14%。欧洲和北美的天疱疮通常发生在50至60岁的成年人中。浅表型很少见(2% - 10%)。在突尼斯,天疱疮与巴西天疱疮相似,发病率高且以浅表型为主(落叶型天疱疮)。