Lavergne T, Sebag C, Ollitrault J, Chouari S, Copie X, Le Heuzey J Y, Guize L
Service de cardiologie A, hôpital Broussais, Paris.
Arch Mal Coeur Vaiss. 1996 Feb;89 Spec No 1:57-63.
Radiofrequency currents are the reference physical agent for endocavitary ablation, especially of supraventricular tachycardias. They are delivered in a continuous mode or sinusoidal waves. Because of the high frequency between 200 and 3,000 kHz there is no stimulation of the neuromuscular cells. The mechanism of the resulting lesion is essentially related to heating of the biological surroundings of the active electrode. The temperature increase remains localised around the active electrode and its kinetics are progressive, which implies close and stable contact between the active electrode and the tissues. The lesional effect is obtained 60 to 90 degrees C in order to avoid the deleterious effects induced by temperatures of over 100 degrees C: boiling, coagulation, vaporization and carbonization of the tissues leading to an increase in impedence. The volume of lesions depends on many factors which are sometimes difficult to control in vivo. It is more closely correlated to the temperature of the active electrode than to the parameters of delivery (power, duration ...). The histological lesions correspond to scar tissue which respects the surrounding architecture. The major technological innovations of this method have resulted in an increase in the volume of the lesions produced, a reduction in the frequency of undesirable effects such as the formation of coagulum and in an immediate evaluation of the anatomic lesional effect. They have consisted in the introduction of specific electrodes and of systems of monitoring the electrical and thermal effects with the use of imaging techniques such as endovascular and transoesophageal echocardiography and angioscopy. New indications will require development of specific catheter-generator equipment to create lesions of size and shape adapted to the arrhythmogenic substrate.
射频电流是腔内消融尤其是室上性心动过速消融的参考物理介质。它们以连续模式或正弦波形式输送。由于频率在200至3000千赫兹之间,不会刺激神经肌肉细胞。产生损伤的机制主要与有源电极周围生物组织的加热有关。温度升高局限于有源电极周围,其动力学是渐进的,这意味着有源电极与组织之间要有紧密且稳定的接触。为避免超过100摄氏度的温度所产生的有害影响(组织沸腾、凝固、汽化和碳化导致阻抗增加),需将损伤效应控制在60至90摄氏度。损伤的体积取决于许多因素,这些因素在体内有时难以控制。它与有源电极的温度比与输送参数(功率、持续时间等)的相关性更强。组织学损伤对应于尊重周围结构的瘢痕组织。该方法的主要技术创新导致所产生损伤的体积增加、诸如形成凝块等不良效应的频率降低以及对解剖学损伤效应的即时评估。这些创新包括引入特定电极以及利用血管内和经食管超声心动图及血管镜等成像技术监测电和热效应的系统。新的适应症将需要开发特定的导管 - 发生器设备,以制造尺寸和形状适合致心律失常基质的损伤。