Bulckaen E, Woestelandt H, Le Borgne J M, Chanteau C
Département d'anesthésie-réanimation, centre hospitalier, Laon, France.
Ann Fr Anesth Reanim. 1996;15(2):202-3. doi: 10.1016/0750-7658(96)85045-3.
A 75 year-old woman was admitted for a myxoedematous coma. Treatment included a prophylactic administration of low molecular weight heparin. During recovery from coma she experienced pain in her right calf. The anticoagulant therapy was switched to subcutaneous calcium heparin. However, the latter had to be discontinued due to the formation of a haematoma of a thigh. Clinical and biological data were in favour of a mechanism of heparin stocking during coma followed by its release during recovery.
一名75岁女性因黏液性水肿昏迷入院。治疗措施包括预防性给予低分子量肝素。在昏迷恢复期间,她感到右小腿疼痛。抗凝治疗改为皮下注射肝素钙。然而,由于大腿出现血肿,后者不得不停用。临床和生物学数据支持昏迷期间肝素蓄积、恢复期间释放的机制。