Graciela Garcia M, Leanza H, Najun Zarazga C, Barreneche M
Instituto de Nefrologia, Buenos Aires.
Medicina (B Aires). 1996;56(1):59-62.
A patient with end-stage renal disease, hemodialysis treatment, severe secondary hyperparathyroidism and mandibular brown tumor received increasing doses of oral calcitriol (3.5 to 9 micrograms/week) and calcium carbonate (10 g/day). Nineteen months after the treatment, clinical, radiological and humoral improvement were observed. The present case demonstrates the effectiveness of medical parathyroidectomy for the control of severe secondary hyperparathyroidism--brown tumor--in chronic hemodialysed patients. This procedure should be considered as choice treatment keeping surgical parathyroidectomy for cases in which it is contraindicated such as hyperphosphoremia and/or controlled hypercalcemia or failure of the former procedure.
一名患有终末期肾病、接受血液透析治疗、重度继发性甲状旁腺功能亢进和下颌棕色瘤的患者,接受了逐渐增加剂量的口服骨化三醇(3.5至9微克/周)和碳酸钙(10克/天)治疗。治疗19个月后,观察到临床、影像学和体液指标均有改善。本病例证明了药物性甲状旁腺切除术对控制慢性血液透析患者的重度继发性甲状旁腺功能亢进——棕色瘤——有效。对于诸如高磷血症和/或可控性高钙血症或前者治疗失败等禁忌手术甲状旁腺切除术的病例,该方法应被视为首选治疗方法。