Nicholson J C, Darmady J M, Kohler J A
Department of Child Health, Southampton General Hospital, UK.
Pediatr Hematol Oncol. 1996 May-Jun;13(3):287-91. doi: 10.3109/08880019609030829.
A girl with acute lymphoblastic leukemia in remission had two seizures during the maintenance phase of her treatment. Magnetic resonance imaging with angiography identified a superior sagittal sinus thrombosis as the likely explanation for her symptoms. Possible causes are considered, and previous reports of the neurotoxicity of agents used in the treatment of leukemia are reviewed.
一名处于缓解期的急性淋巴细胞白血病女孩在治疗维持阶段出现了两次癫痫发作。磁共振血管造影成像确定上矢状窦血栓形成可能是其症状的原因。文中考虑了可能的病因,并回顾了先前关于白血病治疗所用药物神经毒性的报告。