Colacurci N, De Placido G, Mollo A, Carravetta C, De Franciscis P
2nd Department of Gynecology and Obstetrics, School of Medicine, Second University of Naples, Italy.
Eur J Obstet Gynecol Reprod Biol. 1996 Jun;66(2):147-50. doi: 10.1016/0301-2115(96)02417-7.
To evaluate the reproductive outcome after hysteroscopic metroplasty.
We analysed the reproductive outcome of 69 patients, with different degrees of septate uterus, undergoing hysteroscopic metroplasty in the outpatient infertility clinic of Naples 'Federico II' University. Of the 69 patients, 48 had a history of recurrent abortion while 21 had a primary infertility. In all cases the procedure was performed by means of the resectoscope.
In 97.1% of the cases post-operative hysterosalpingogram or hysteroscopic examination showed a normal cavity with a little fundal notch. In two cases, second surgery was needed. Of the 48 patients affected by repeated abortion, 40 became pregnant after the metroplasty whereas, to date, in the infertile group only six out 21 (29.0%) conceived. We observed a total of 46 pregnancies with two sets of twins. Of these, 31 pregnancies (67.4%) were carried to term, five (10.8%) ended in preterm delivery, six (13%) ended in spontaneous abortion and four (8.6%) are in progress. Cervical cerclage was performed on 13 women. Only one (7.6%) woman with cervical cerclage had a preterm delivery, while the preterm delivery rate in women without cerclage was 12.1%. The modality of term pregnancy deliveries was cesarean section in 48% of the cases and vaginal delivery in the 52%.
Our data analysis suggest that the correction of mullerian anomalies does not improve the pregnancy rate, but only the pregnancy outcome of the patients.
评估宫腔镜子宫成形术后的生殖结局。
我们分析了那不勒斯“费德里科二世”大学门诊不孕不育诊所中69例不同程度纵隔子宫患者接受宫腔镜子宫成形术的生殖结局。69例患者中,48例有反复流产史,21例为原发性不孕。所有病例均通过电切镜进行手术。
97.1%的病例术后子宫输卵管造影或宫腔镜检查显示宫腔正常,仅有少许宫底切迹。2例患者需要二次手术。48例反复流产患者中,40例子宫成形术后怀孕;而截至目前,在不孕组中,21例患者仅有6例(29.0%)受孕。我们共观察到46次妊娠,其中有两对双胞胎。其中,31例妊娠(67.4%)足月分娩,5例(10.8%)早产,6例(13%)自然流产,4例(8.6%)仍在继续妊娠。13名女性接受了宫颈环扎术。仅1例(7.6%)接受宫颈环扎术的女性早产,而未接受环扎术的女性早产率为12.1%。足月妊娠分娩方式中,48%为剖宫产,52%为阴道分娩。
我们的数据分析表明,苗勒氏管异常的矫正并不能提高妊娠率,而仅能改善患者的妊娠结局。