Martinowitz U, Schulman S
Division of Hematology, National Hemophilia Center, Tel-Hashomer, Israel.
Blood Coagul Fibrinolysis. 1996 Mar;7 Suppl 1:S27-33.
Continuous infusion of coagulation factor concentrates has become more popular in recent years because it can substantially reduce the cost of surgery for a patient with hemophilia. This technique has also been used successfully for treatment of severe bleeds, induction of immune tolerance and short-term prophylaxis. The large selection of devices complicates the choice of an infusion system for this delivery approach. However, choosing the best type of device for a particular situation may determine the success or failure of continuous infusion.
近年来，凝血因子浓缩物的持续输注越来越普遍，因为它可以大幅降低血友病患者的手术成本。该技术也已成功用于治疗严重出血、诱导免疫耐受和短期预防。大量可供选择的设备使为这种给药方式选择输注系统变得复杂。然而，为特定情况选择最佳类型的设备可能决定持续输注的成败。
