Bjørnstad K, al Amri M, Lingamanaicker J, Oqaili I, Hatle L
Department of Cardiovascular Diseases, King Faisal Specialist Hospital and Research Centre, Riyadh, Kingdom of Saudi Arabia.
J Am Soc Echocardiogr. 1996 May-Jun;9(3):320-8. doi: 10.1016/s0894-7317(96)90147-9.
Interobserver and intraobserver variation for analysis of left ventricular regional wall motion during dobutamine stress echocardiography was assessed. Computer-displayed cineloops from 33 patients, 25 with baseline wall motion abnormalities, were analyzed by two observers blinded for patient data. Assessment included (1) baseline wall motion abnormalities, (2) evidence of myocardial viability at 10 micrograms/kg/min dobutamine, and (3) evidence of myocardial ischemia at 30 to 40 micrograms/kg/min. Wall motion score index was calculated at each stage. Interobserver and intraobserver agreement for baseline wall motion abnormalities was 100%. Interobserver agreement for viability and ischemia was 84% and 82%, respectively; intraobserver agreement was 92% and 85%, respectively. Mean interobserver differences in wall motion score index ranged from 0.06 +/- 0.14 at baseline to 0.09 +/- 0.20 at high doses (p < 0.05 at all levels); mean intraobserver differences ranged from 0.001 +/- 0.14 to 0.01 +/- 0.15 (difference not significant at all levels).
评估了多巴酚丁胺负荷超声心动图检查期间左心室节段性室壁运动分析的观察者间和观察者内差异。由两名对患者数据不知情的观察者对33例患者（其中25例有基线室壁运动异常）的计算机显示的电影环进行分析。评估内容包括：（1）基线室壁运动异常；（2）多巴酚丁胺剂量为10微克/千克/分钟时的心肌存活证据；（3）多巴酚丁胺剂量为30至40微克/千克/分钟时的心肌缺血证据。在每个阶段计算室壁运动评分指数。观察者间和观察者内对基线室壁运动异常的一致性为100%。观察者间对存活和缺血的一致性分别为84%和82%；观察者内一致性分别为92%和85%。室壁运动评分指数的观察者间平均差异范围从基线时的0.06±0.14到高剂量时的0.09±0.20（所有水平p<0.05）；观察者内平均差异范围从0.001±0.14到0.01±0.15（所有水平差异均无统计学意义）。
