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HLA antigens and erythrocyte glucose-6-phosphate dehydrogenase (G-6-PD) deficiency in Sardinia.

作者信息

Carcassi U, Del Giacco G S, Pintus A, Perpignano G, Locci F, Loy M, Batzella M G, Piludu G, Cengiarotti L, Ibba G, Leone A L

出版信息

Int Arch Allergy Appl Immunol. 1977;54(3):285-7. doi: 10.1159/000231838.

DOI:10.1159/000231838
PMID:873627
Abstract

The frequency of 17 HLA antigens from locus A and locus B has been evaluated by microlymphocytotoxicity test in a population of 233 subjects (157 normal and 76 with deficiency of glucose-6-phosphate dehydrogenase [G-6PD]in red cells) from a village of Sardinia, a mediterranean island relatively close to continental Italy. It appears that G-6-PD-deficient people show a frequency of some HLA antigens (A2, A10, B12, BW35) significatively different from normal Sardinian subjects but close to (A10, BW35) or higher (A2, B12) than that of subjects from peninsular Italy.

摘要

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