Miyagawa S, Fukumoto T, Kanauchi M, Masunaga I, Fujimoto T, Dohi K, Shirai T
Department of Dermatology, Nara Medical University, Kashihara City, Japan.
Br J Dermatol. 1996 May;134(5):919-23.
Seven out of nine patients (78%), seen over a 13-year period with hypergammaglobulinaemic purpura of Waldenström were found to have antibodies to Ro/SSA. Over this period we saw 175 patients who had antibodies to Ro/SSA. In six of the seven patients, associated diseases were recognized. Five had Sjögren's syndrome, and one had systemic lupus erythematosus with Sjögren's syndrome and thyroiditis (and died 19 years after initial presentation from cerebral infarction). Screening for antibodies to Ro/SSA is important in the diagnosis of patients with hypergamma-globulinaemic purpura, and is helpful in predicting prognosis.
在13年期间诊治的9例瓦尔登斯特伦高丙种球蛋白血症性紫癜患者中，有7例（78%）被发现存在抗Ro/SSA抗体。在此期间，我们共诊治了175例存在抗Ro/SSA抗体的患者。在这7例患者中的6例中，发现了相关疾病。5例患有干燥综合征，1例患有系统性红斑狼疮合并干燥综合征和甲状腺炎（初次就诊19年后死于脑梗死）。对抗Ro/SSA抗体进行筛查对于高丙种球蛋白血症性紫癜患者的诊断很重要，并且有助于预测预后。
