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The metabolic role of GIP: physiology and pathology.

作者信息

Morgan L M

机构信息

School of Biological Sciences, University of Surrey, Guildford, U.K.

出版信息

Biochem Soc Trans. 1996 May;24(2):585-91. doi: 10.1042/bst0240585.

DOI:10.1042/bst0240585
PMID:8736808
Abstract
摘要

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The metabolic role of GIP: physiology and pathology.葡萄糖依赖性促胰岛素多肽的代谢作用:生理学与病理学
Biochem Soc Trans. 1996 May;24(2):585-91. doi: 10.1042/bst0240585.
2
[GIP and GLP-1: multiplicity of regulator mechanisms for insulin secretion].[胃抑肽和胰高血糖素样肽-1:胰岛素分泌调节机制的多样性]
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GIP and GLP-1 as incretin hormones: lessons from single and double incretin receptor knockout mice.作为肠促胰岛素激素的葡萄糖依赖性促胰岛素多肽(GIP)和胰高血糖素样肽-1(GLP-1):来自单和双肠促胰岛素受体敲除小鼠的经验教训。
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Gastric inhibitory polypeptide and glucagon-like peptide-1 in the pathogenesis of type 2 diabetes.胃抑制多肽和胰高血糖素样肽-1在2型糖尿病发病机制中的作用
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6
Glucagon-like peptide-1 and control of insulin secretion.胰高血糖素样肽-1与胰岛素分泌的调控
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Treatment of type 2 diabetes mellitus with agonists of the GLP-1 receptor or DPP-IV inhibitors.使用胰高血糖素样肽-1受体激动剂或二肽基肽酶-IV抑制剂治疗2型糖尿病。
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Central glucagon-like peptide-I in the control of feeding.
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Localization of the domains involved in ligand binding and activation of the glucose-dependent insulinotropic polypeptide receptor.参与葡萄糖依赖性促胰岛素多肽受体配体结合和激活的结构域的定位。
Endocrinology. 1997 Jun;138(6):2640-3. doi: 10.1210/endo.138.6.9104.
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Reduction of the incretin effect in rats by the glucagon-like peptide 1 receptor antagonist exendin (9-39) amide.胰高血糖素样肽-1受体拮抗剂艾塞那肽(9-39)酰胺降低大鼠肠促胰岛素效应
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Effects of the novel (Pro3)GIP antagonist and exendin(9-39)amide on GIP- and GLP-1-induced cyclic AMP generation, insulin secretion and postprandial insulin release in obese diabetic (ob/ob) mice: evidence that GIP is the major physiological incretin.新型(Pro3)GIP拮抗剂和艾塞那肽(9 - 39)酰胺对肥胖糖尿病(ob/ob)小鼠中GIP和GLP - 1诱导的环磷酸腺苷生成、胰岛素分泌及餐后胰岛素释放的影响:GIP是主要生理性肠促胰岛素的证据
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Detection of glycated gastric inhibitory polypeptide within the intestines of diabetic obese (ob/ob) mice.在糖尿病肥胖(ob/ob)小鼠肠道内检测糖化胃抑制多肽。
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