Pérez-Díaz C J, Villarejo F J, Pascual A M
Department of Neurosurgery, Hospital del Nino Jesús, Madrid, Spain.
Childs Nerv Syst. 1996 May;12(5):283-6; discussion 287. doi: 10.1007/BF00261813.
Two cases of trigeminal neurinoma in two infant girls aged 3 and 6 months are reported. Both presented with temporal cranial vault bulging at birth. The 6-month-old patient suffered onset of focal fits 1 month before admission and her neurological examination revealed no abnormalities. The 3-month-old patient had right exophthalmus and a subcutaneous fronto-orbital plexiform neurofibroma at birth. Neurological examination disclosed a sensory deficit of the first trigeminal nerve division. She also had a family medical history of von Reckling-hausen's disease. The incidence of trigeminal neurinomas in children is reviewed. The patients in these two cases are the youngest recorded; the cases are the only ones reported in infants. Clinical, radiological, and therapeutic aspects are discussed.
报告了两例分别为3个月和6个月大女婴的三叉神经鞘瘤病例。两名患儿出生时均表现为颞顶部颅骨膨隆。6个月大的患儿在入院前1个月出现局灶性惊厥发作，其神经系统检查未发现异常。3个月大的患儿出生时即有右眼突出及皮下额眶部丛状神经纤维瘤。神经系统检查发现三叉神经第一分支感觉缺失。她还有冯·雷克林豪森病的家族病史。本文回顾了儿童三叉神经鞘瘤的发病率。这两例患者是有记录以来最年幼的；这些病例是仅有的婴儿期报道病例。文中还讨论了临床、影像学及治疗方面的情况。
