Boutin R D, Spaeth H J, Mangalik A, Sell J J
Department of Radiology, University of New Mexico, School of Medicine, Albuquerque 87131-53362, USA.
Skeletal Radiol. 1996 May;25(4):391-5. doi: 10.1007/s002560050102.
Neoplasms of bone can arise from any of the cellular elements that constitute osseous tissues. Although tumors of vascular origin are not uncommon, the vast majority are benign. A rare malignant vascular tumor--epithelioid hemangioendothelioma of bone--classifically affects young males and produces osteolytic lesions involving the cortex and cancellous bone of the lower extremities. We present a case with these findings, as well as such unusual findings as cervical spine instability and lesions affecting no fewer than 45 different bones. We conclude that epithelioid hemangioendothelioma should be investigated by skeletal survey because (1) osteolytic lesions involving more that 50% of the cortex present a serious risk for pathologic fracture and (2) the natural history of multicentric epithelioid hemangioendothelioma is more indolent than its solitary counterparts.
骨肿瘤可起源于构成骨组织的任何细胞成分。虽然血管源性肿瘤并不罕见，但绝大多数是良性的。一种罕见的恶性血管肿瘤——骨上皮样血管内皮瘤——典型地影响年轻男性，并产生累及下肢皮质和松质骨的溶骨性病变。我们报告了一例具有这些表现的病例，以及诸如颈椎不稳定和累及不少于45块不同骨骼的病变等不寻常表现。我们得出结论，对于上皮样血管内皮瘤应进行骨骼检查，因为（1）累及超过50%皮质的溶骨性病变存在病理性骨折的严重风险，且（2）多中心性上皮样血管内皮瘤的自然病程比单发性者更为隐匿。
