垂体腺瘤的当前病理分类。

Current pathological classification of pituitary adenomas.

作者信息

Saeger W

机构信息

Department of Pathology, Marienkrankenhaus, Hamburg, Federal Republic of Germany.

出版信息

Acta Neurochir Suppl. 1996;65:1-3. doi: 10.1007/978-3-7091-9450-8_1.

DOI:10.1007/978-3-7091-9450-8_1

PMID:8738481

Abstract

A classification of pituitary adenomas basing on detailed structural and immunohistochemical studies is accepted world-wide and is mandatory for each pathologist. Monohormonal (densely or sparsely granulated GH cell adenomas, Prolactin cell adenomas, ACTH cell adenomas. FSH/LH cell adenomas, alpha-subunit-only adenomas), bihormonal (mixed GH/Prolactin cell adenomas, mammosomatotroph cell adenomas, acidophil stem cell adenomas), plurihormonal (GH/Prolactin/Glycoprotein-positive adenomas, other Glycoprotein-positive types) and hormone-negative adenomas (null cell adenomas, oncocytic adenomas) have to be differentiated.

摘要

基于详细的结构和免疫组化研究的垂体腺瘤分类在全球范围内被广泛接受，并且是每位病理学家的必备知识。单激素型（密集或稀疏颗粒状生长激素细胞腺瘤、催乳素细胞腺瘤、促肾上腺皮质激素细胞腺瘤、促卵泡激素/促黄体生成素细胞腺瘤、仅α亚单位腺瘤）、双激素型（混合生长激素/催乳素细胞腺瘤、乳腺生长激素细胞腺瘤、嗜酸性干细胞腺瘤）、多激素型（生长激素/催乳素/糖蛋白阳性腺瘤、其他糖蛋白阳性类型）和激素阴性腺瘤（无功能细胞腺瘤、嗜酸性细胞瘤）必须加以区分。