Lykouras L, Adrachta D, Kalfakis N, Oulis P, Voulgari A, Christodoulou G N, Papageorgiou C, Stefanis C
Department of Psychiatry, University of Athens, Eginition Hospital, Greece.
Acta Psychiatr Scand. 1996 Mar;93(3):212-6. doi: 10.1111/j.1600-0447.1996.tb10634.x.
The prevalence of mental disorders (DSM-IIIR criteria) among 107 neurological inpatients was estimated, as well as the extent to which disorders were detected by neurologists. The validity of the scaled version of the General Health Questionnaire (GHQ-28) was evaluated using Receiver Operating Characteristic (ROC) analysis and DSM-IIIR as external criteria. Of the 107 patients who submitted to a structured psychiatric interview (SCID-R), 56 (52.3%) showed evidence of a mental disorder. Major depressive episode (n = 16), generalized anxiety disorders (n = 13) and dysthymia (n = 12) were the most frequent diagnoses. The neurologists recognized only 13/107 cases (12.1%). Significantly more women than men exhibited some form of mental disorder. The validation of GHQ-28 in the series of 107 neurological inpatients indicated that the best trade-off between sensitivity and specificity was the cut-off score of 5/6. The high occurrence of mental disorder, in association with the low rate of detection by the neurologists, points to the need for special attention to be paid to this problem by staff and experts.
对107名神经科住院患者的精神障碍患病率（采用《精神疾病诊断与统计手册》第三版修订本（DSM-IIIR）标准）进行了估算，并评估了神经科医生对这些疾病的检出程度。使用接受者操作特征（ROC）分析并以DSM-IIIR作为外部标准，对一般健康问卷简版（GHQ-28）的有效性进行了评估。在接受结构化精神科访谈（SCID-R）的107名患者中，56名（52.3%）有精神障碍的证据。重度抑郁发作（n = 16）、广泛性焦虑障碍（n = 13）和心境恶劣（n = 12）是最常见的诊断。神经科医生仅识别出13/107例（12.1%）。患有某种形式精神障碍的女性明显多于男性。对107名神经科住院患者系列中GHQ-28的验证表明，敏感性和特异性之间的最佳权衡是临界值为5/6。精神障碍的高发病率，加上神经科医生的低检出率，表明工作人员和专家需要特别关注这个问题。
