Kagawa H, Yasuzawa M, Ozaki Y, Yamamoto Y, Katsurada T, Nomura S, Okubo S, Fukuhara S
First Department of Internal Medicine, Kansai Medical University, Osaka.
Intern Med. 1996 Apr;35(4):319-22. doi: 10.2169/internalmedicine.35.319.
A 28-year-old severe hemophiliac with a factor VIII inhibitor was admitted to our hospital with a massive and serious intraperitoneal hematoma. He was a high-responder patient showing maximal serum inhibitor levels as high as 255 Bethesda Units/ml (BU/ml). He was successfully treated with "bypass therapy" using a prothrombin complex concentrate (PCC).