Carrel T, Niederhäuser U, Turina M
Klinik für Herz- und Gefässchirurgie, Universitätsspital Zürich.
Schweiz Med Wochenschr. 1995 Feb 11;125(6):212-6.
Refinement in surgical technique and perioperative management have considerably improved morbidity and mortality rates of carotid endarterectomy and abdominal aortic surgery, thus allowing a more aggressive approach in the treatment of carotid stenosis, abdominal aortic aneurysm and aorto-iliac occlusive disease in the elderly population (> 70 years). We review our experience with 446 consecutive patients undergoing surgery of the abdominal aorta: 295 patients (mean age 75.5 years) underwent resection of an abdominal aortic aneurysm (asymptomatic but > 5-6 cm, (n = 193), symptomatic (n = 67) or ruptured (n = 35). Additionally, 198 patients were treated surgically for aorto-iliac occlusive disease. A small group of 13 patients was deferred for combined operation, including prior myocardial revascularization and subsequent vascular surgery during the same anesthesia. The majority of patients had several cardiovascular risk factors and/or significant associated diseases. Mortality (< 30 days) was 3.5% following aorto-iliac bypass in the treatment of arterial occlusive disease and 8.4% after aneurysm repair (asymptomatic, symptomatic and ruptured aneurysms all included). 5-year survival was 74% and 64% after repair of aortic aneurysm and treatment of aorto-iliac occlusive disease respectively. On the basis of these results, we believe that major vascular surgery is still justified in elderly patients and can be achieved with reasonable mortality and morbidity. Main goals of the surgery, e.g. to relieve suffering, restore function so as to limit disability and dependency, and prolongation of life expectancy in a dignified and meaningful life-style, are realized the majority of operative survivors.
手术技术和围手术期管理的改进显著提高了颈动脉内膜切除术和腹主动脉手术的发病率和死亡率,从而使我们能够更积极地治疗老年人群(>70岁)的颈动脉狭窄、腹主动脉瘤和主-髂动脉闭塞性疾病。我们回顾了连续446例接受腹主动脉手术患者的经验:295例患者(平均年龄75.5岁)接受了腹主动脉瘤切除术(无症状但直径>5-6cm,(n=193),有症状(n=67)或破裂(n=35)。此外,198例患者接受了主-髂动脉闭塞性疾病的手术治疗。一小部分13例患者因联合手术而推迟,包括先进行心肌血运重建,随后在同一麻醉下进行血管手术。大多数患者有多种心血管危险因素和/或严重的相关疾病。在治疗动脉闭塞性疾病时,主-髂动脉搭桥术后30天内死亡率为3.5%,动脉瘤修复术后(包括无症状、有症状和破裂的动脉瘤)死亡率为8.4%。腹主动脉瘤修复术和主-髂动脉闭塞性疾病治疗术后5年生存率分别为74%和64%。基于这些结果,我们认为,老年患者进行大血管手术仍然是合理的,并且可以实现合理的死亡率和发病率。手术的主要目标,如减轻痛苦、恢复功能以限制残疾和依赖,并以有尊严和有意义的生活方式延长预期寿命,在大多数手术幸存者中得以实现。