[脑肿瘤、颅脑损伤和脑膜脑炎病例中脑脊液酸碱平衡及脑脊液乳酸浓度的统计分析]

[Statistical analysis of cerebrospinal fluid acid-base equilibrium and cerebrospinal fluid lactate concentration in cases of brain tumors, cerebrocranial injuries and meningoencephalitis].

作者信息

Czernicki Z, Karczewska E, Rycembel Z, Sliwka S, Korsak-Sliwka J

出版信息

Neurol Neurochir Pol. 1976 Jul-Aug;10(4):539-42.

Abstract

A statistical analysis of CSF lactate concentration and CSF pH and PCO2 was performed. The values were obtained from 211 samples taken from 76 neurosurgical patients. The values of pH and pCO2 were classified in three groups corresponding to the following three ranges of lactate concentration: below 15 mg%, 15-30 mg%, over 30 mg%. The mean values and standard deviations were calculated: suitable tests: F, t (Student), C (Cochran and Cox) were used. It was established, that statistically significant changes of CSF acid-base balance were present at lactate levels over 30 mg%. Next, the patients with lactate concentrations over 30 mg% were analysed. They were divided into three groups according to etiology: inflammatory changes, injuries, tumours. It was shown, that the CSF acid-base balance in patients with brain tumours is less disturbed then in patients with inflammatory changes or brain injury.

摘要

对脑脊液乳酸浓度、脑脊液pH值和PCO₂进行了统计分析。这些值取自76名神经外科患者的211份样本。pH值和PCO₂值被分为三组，分别对应以下三个乳酸浓度范围：低于15mg%、15 - 30mg%、高于30mg%。计算了平均值和标准差：使用了合适的检验方法：F检验、t检验（学生t检验）、C检验（ Cochr an和Cox检验）。结果表明，当乳酸水平高于30mg%时，脑脊液酸碱平衡存在统计学上的显著变化。接下来，对乳酸浓度高于30mg%的患者进行了分析。根据病因将他们分为三组：炎症性改变、损伤、肿瘤。结果显示，脑肿瘤患者的脑脊液酸碱平衡比炎症性改变或脑损伤患者受到的干扰更小。