Lüscher C, Rösler K M, Mathis J, Beer S, Hess C W
Department of Neurology, University of Bern, Inselspital, Switzerland.
Exp Brain Res. 1996 Apr;109(1):154-7. doi: 10.1007/BF00228637.
Previous reports suggest that magnetic cortical stimulation (MCS) of the motor cortex can elicit a sensation of movement (kinaesthesia) in paralysed limbs. To assess this sensory effect of MCS, we examined the accuracy of kinaesthetic perception of stimulus-induced right elbow flexion in six blindfolded, healthy subjects. Matching of movements elicited by MCS was compared with matching of passive elbow movements. Small flexion movements between 1.5 and 5 degrees of angle were regularly overestimated by 50-100% when induced by MCS over the parietal cortex, whereas movements elicited by MCS over the frontal cortex or by passive elbow flexion were accurately estimated. Our results provide data compatible with the hypothesis of the existence of a "central sense of movement". Activation of collateral branches projecting from the motor cortex to the sensory could be the underlying mechanism to this phenomenon.
先前的报告表明，对运动皮层进行磁刺激（MCS）能够在瘫痪肢体中引发运动感觉（动觉）。为评估MCS的这种感觉效应，我们对6名蒙眼的健康受试者刺激诱发的右肘屈曲的动觉感知准确性进行了检测。将MCS诱发的运动匹配与被动肘运动的匹配进行了比较。当通过顶叶皮层进行MCS诱发时，1.5至5度角之间的小幅度屈曲运动经常被高估50%至100%，而额叶皮层进行MCS诱发的运动或被动肘屈曲诱发的运动则能被准确估计。我们的结果提供了与“中枢运动感觉”存在假说相符的数据。从运动皮层投射到感觉区的侧支激活可能是这一现象的潜在机制。
