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急诊科中的神经肌肉阻滞剂

Neuromuscular blocking agents in the emergency department.

作者信息

Rubin M A, Sadovnikoff N

机构信息

Department of Emergency Medicine, Johns Hopkins Medical Institutions, Baltimore, MD 21287-2080, USA.

出版信息

J Emerg Med. 1996 Mar-Apr;14(2):193-9. doi: 10.1016/0736-4679(95)02105-1.

DOI:10.1016/0736-4679(95)02105-1
PMID:8740751
Abstract

Neuromuscular blocking agents (NMBAs) are utilized frequently in the emergency department (ED). We begin with a brief history of neuromuscular blockade, then review the indications and guidelines for its use in the emergency department setting. The relevant agents will be discussed focusing on dosage, side effects, and adverse reactions. Special attention will be paid to succinylcholine, the drug most commonly employed in the ED setting, followed by a summary of the nondepolarizing agents currently available, in particular the four shorter-acting agents that are most appropriate for administration in the ED.

摘要

神经肌肉阻滞剂(NMBAs)在急诊科(ED)中经常使用。我们首先简要介绍神经肌肉阻滞的历史,然后回顾其在急诊科环境中使用的适应症和指南。将重点讨论相关药物的剂量、副作用和不良反应。将特别关注琥珀酰胆碱,这是急诊科最常用的药物,随后总结目前可用的非去极化剂,特别是四种最适合在急诊科使用的短效剂。

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1
Neuromuscular blocking agents in the emergency department.急诊科中的神经肌肉阻滞剂
J Emerg Med. 1996 Mar-Apr;14(2):193-9. doi: 10.1016/0736-4679(95)02105-1.
2
Succinylcholine: adverse effects and alternatives in emergency medicine.琥珀酰胆碱:急诊医学中的不良反应及替代药物
Am J Emerg Med. 1999 Nov;17(7):715-21. doi: 10.1016/s0735-6757(99)90168-7.
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[Muscle relaxants in the ICU].[重症监护病房中的肌肉松弛剂]
Anasthesiol Intensivmed Notfallmed Schmerzther. 2009 May;44(5):358-64; quiz 366, 379. doi: 10.1055/s-0029-1224783. Epub 2009 May 13.
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Nondepolarizing neuromuscular blocking drugs in the intensive care unit: a clinical review.
South Med J. 1997 Aug;90(8):769-74. doi: 10.1097/00007611-199708000-00001.
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Rocuronium bromide in dental day case anaesthesia--a comparison with atracurium and vecuronium.牙科日间手术麻醉中使用的罗库溴铵——与阿曲库铵和维库溴铵的比较
Anaesth Intensive Care. 1996 Feb;24(1):37-41.
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Rocuronium vs. succinylcholine in the emergency department: a critical appraisal.急诊科中罗库溴铵与琥珀酰胆碱的比较:一项批判性评估。
J Emerg Med. 2009 Aug;37(2):183-8. doi: 10.1016/j.jemermed.2008.07.021. Epub 2008 Dec 20.
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Newer neuromuscular blocking agents: how do they compare with established agents?新型神经肌肉阻滞剂:与现有药物相比如何?
Drugs. 2001;61(7):919-42. doi: 10.2165/00003495-200161070-00003.
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Rocuronium vs. succinylcholine revisited.罗库溴铵与琥珀酰胆碱再探讨。
J Emerg Med. 2010 Sep;39(3):345-6; author reply 346-7. doi: 10.1016/j.jemermed.2009.08.070. Epub 2010 Apr 24.
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Skin reactions to intradermal neuromuscular blocking agent injections: a randomized multicenter trial in healthy volunteers.皮内注射神经肌肉阻滞剂的皮肤反应:一项在健康志愿者中的随机多中心试验。
Anesthesiology. 2007 Aug;107(2):245-52. doi: 10.1097/01.anes.0000270721.27309.b3.
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A comparison of succinylcholine and rocuronium for rapid-sequence intubation of emergency department patients.急诊科患者快速顺序插管时琥珀酰胆碱与罗库溴铵的比较。
Acad Emerg Med. 2000 Dec;7(12):1362-9. doi: 10.1111/j.1553-2712.2000.tb00493.x.

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