Boersma B, Otten B J, Stoelinga G B, Wit J M
Department of Paediatrics, University Hospital Leiden, The Netherlands.
Eur J Pediatr. 1996 May;155(5):362-7. doi: 10.1007/BF01955262.
This report presents an analysis of four patients who suffered from longstanding untreated hypothyroidism, with special attention to the phase of catch-up growth after the start of L-thyroxine treatment. Although a permanent height loss could not be prevented, the capacity to establish a remarkable catch-up growth spurt proved to be still intact, even after a long period of thyroid dysfunction.
Catch-up growth in hypothyroidism may be incomplete if treatment has been started shortly before or during puberty.
本报告分析了4例长期未经治疗的甲状腺功能减退患者,特别关注左甲状腺素治疗开始后的追赶生长阶段。尽管无法预防永久性身高损失,但即使经过长时间的甲状腺功能障碍,建立显著追赶生长突增的能力仍未受损。
如果在青春期前不久或青春期期间开始治疗,甲状腺功能减退症的追赶生长可能不完全。